BRL-54443
Encyclopedia
BRL-54443 is a drug which acts as a selective agonist
for the 5-HT1E
and 5-HT1F serotonin
receptor
subtypes.
Agonist
An agonist is a chemical that binds to a receptor of a cell and triggers a response by that cell. Agonists often mimic the action of a naturally occurring substance...
for the 5-HT1E
5-HT1E receptor
5-hydroxytryptamine 1E receptor is a highly expressed human G-protein coupled receptor that belongs to the 5-HT1 receptor family . The human gene is denoted as HTR1E.-Function:...
and 5-HT1F serotonin
Serotonin
Serotonin or 5-hydroxytryptamine is a monoamine neurotransmitter. Biochemically derived from tryptophan, serotonin is primarily found in the gastrointestinal tract, platelets, and in the central nervous system of animals including humans...
receptor
Receptor (biochemistry)
In biochemistry, a receptor is a molecule found on the surface of a cell, which receives specific chemical signals from neighbouring cells or the wider environment within an organism...
subtypes.