BRL-52537
Encyclopedia
BRL-52537 is a drug which acts as a potent and highly selective κ-opioid
agonist
. It has neuroprotective effects in animal studies, and is used for research into potential treatments for stroke
and heart attack as well as more general brain research.
Kappa Opioid receptor
The κ-opioid receptor is a protein that in humans is encoded by the OPRK1 gene. The κ-opioid receptor is one of five related receptors that bind opium-like compounds in the brain and are responsible for mediating the effects of these compounds...
agonist
Agonist
An agonist is a chemical that binds to a receptor of a cell and triggers a response by that cell. Agonists often mimic the action of a naturally occurring substance...
. It has neuroprotective effects in animal studies, and is used for research into potential treatments for stroke
Stroke
A stroke, previously known medically as a cerebrovascular accident , is the rapidly developing loss of brain function due to disturbance in the blood supply to the brain. This can be due to ischemia caused by blockage , or a hemorrhage...
and heart attack as well as more general brain research.