Augustin Grisolle
Encyclopedia
Augustin Grisolle was a French physician born in Fréjus
Fréjus
Fréjus is a commune in the Var department in the Provence-Alpes-Côte d'Azur region in southeastern France.It neighbours Saint-Raphaël, effectively forming one town...

.

Grisolle was a professor to the Paris
Paris
Paris is the capital and largest city in France, situated on the river Seine, in northern France, at the heart of the Île-de-France region...

 faculty of medicine and a member of the Académie de Médecine. He was the author of the two-volume Traité élémentaire et pratique de pathologie interne (1844).

His name is associated with "Grisolle's sign", an obsolete sign once affiliated with smallpox
Smallpox
Smallpox was an infectious disease unique to humans, caused by either of two virus variants, Variola major and Variola minor. The disease is also known by the Latin names Variola or Variola vera, which is a derivative of the Latin varius, meaning "spotted", or varus, meaning "pimple"...

. It involved feeling the presence of papules when the skin is stretched.

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