Arkansas Highway 151 is a designation for two north–south state highways in Mississippi County, Arkansas. An eastern route of 5.75 miles (9.3 km) runs from Highway 148

Arkansas Highway 148

-Section 1:Arkansas Highway 148 is a state highway of that runs in Mississippi County.-Route description:AR 148 begins at AR 181 and crosses over Interstate 55 as Exit 57...

 north to Highway 18

Arkansas Highway 18

Arkansas Highway 18 is a state highway of in Northeastern Arkansas.-Route description:AR 18 begins at AR 69 near Jacksonport. Brief concurrencies begins with AR 17 and US 67 in Newport, and Arkansas Highway 18 Spur leads to Newport Municipal Airport as AR 18 continues east. The route runs east to...

. A second route of 6.65 miles (10.7 km) begins at Highway 18 in Blytheville

Blytheville, Arkansas

Blytheville is the largest city in and one of the two county seats of Mississippi County, Arkansas, United States. The population was 15,620 at the 2010 census....

 and runs north to Missouri supplemental route TT

Missouri Supplemental Route

A supplemental route is a state secondary road in the U.S. state of Missouri, designated with letters. Supplemental routes were various roads within the state which the Missouri Department of Transportation was given in 1952 to maintain in addition to the regular routes...

 (SSR-TT) at the Missouri

Missouri

Missouri is a US state located in the Midwestern United States, bordered by Iowa, Illinois, Kentucky, Tennessee, Arkansas, Oklahoma, Kansas and Nebraska. With a 2010 population of 5,988,927, Missouri is the 18th most populous state in the nation and the fifth most populous in the Midwest. It...

 state line.

Highway 148 to Blytheville

The route begins at Highway 148

Arkansas Highway 148

-Section 1:Arkansas Highway 148 is a state highway of that runs in Mississippi County.-Route description:AR 148 begins at AR 181 and crosses over Interstate 55 as Exit 57...

 southeast of Blytheville

Blytheville, Arkansas

Blytheville is the largest city in and one of the two county seats of Mississippi County, Arkansas, United States. The population was 15,620 at the 2010 census....

 and runs north near Promised Land to intersect the eastern end of Highway 312

Arkansas Highway 312

Arkansas Highway 18 is a state highway of in Mississippi County.-Route description:AR 312 begins at AR 18 south of Blytheville. The route runs east cross over I-55, followed by a junction with US 61/AR 148. AR 148/AR 312 concur east until AR 312 turns north with AR 239...

 at the Blytheville city limits. Highway 151 continues north into Blytheville over the BNSF railroad tracks

BNSF Railway

The BNSF Railway is a wholly owned subsidiary of Berkshire Hathaway Inc., and is headquartered in Fort Worth, Texas. It is one of seven North American Class I railroads and the second largest freight railroad network in North America, second only to the Union Pacific Railroad, its primary...

 to terminate at Highway 18

Arkansas Highway 18

Arkansas Highway 18 is a state highway of in Northeastern Arkansas.-Route description:AR 18 begins at AR 69 near Jacksonport. Brief concurrencies begins with AR 17 and US 67 in Newport, and Arkansas Highway 18 Spur leads to Newport Municipal Airport as AR 18 continues east. The route runs east to...

.

Blytheville to Missouri

Highway 151 begins at Highway 18 (Main Street) in Blytheville and runs north to Gosnell

Gosnell, Arkansas

Gosnelle is a city in Mississippi County, Arkansas, United States. The population was 3,968 at the 2000 census.-Geography:Gosnelle used to depend on the nearby Blytheville/Eaker Air Force Base but since its closing in the early 1990s, the city has lost many of its inhabitants...

 and Arkansas International Airport

Arkansas International Airport

Arkansas International Airport is a public use airport located three nautical miles northwest of the central business district of Blytheville, a city in Mississippi County, Arkansas, United States...

. The route intersects and forms a concurrency

Concurrency (road)

A concurrency, overlap, or coincidence in a road network is an instance of one physical road bearing two or more different highway, motorway, or other route numbers...

 with Highway 181

Arkansas Highway 181

Arkansas Highway 181 is the name for two different state highways in Mississippi County.-Section 1:Arkansas Highway 148 is a state highway of that runs in Mississippi County.-Route description:...

 northwest for 2.04 miles (3.3 km), with Highway 151 splitting north to terminate at Missouri supplemental route TT

Missouri Supplemental Route

A supplemental route is a state secondary road in the U.S. state of Missouri, designated with letters. Supplemental routes were various roads within the state which the Missouri Department of Transportation was given in 1952 to maintain in addition to the regular routes...

 at the Missouri

Missouri

Missouri is a US state located in the Midwestern United States, bordered by Iowa, Illinois, Kentucky, Tennessee, Arkansas, Oklahoma, Kansas and Nebraska. With a 2010 population of 5,988,927, Missouri is the 18th most populous state in the nation and the fifth most populous in the Midwest. It...

state line.

Major intersections

Mile markers reset at concurrencies.
|-
| align=center colspan=3 | Highway 151 begins at Highway 18
|-