Area composita
Encyclopedia
The area composita is a special heart
muscle specific mixed type adhering junction connecting single cardiomyocytes. They are responsible for the force transmission during muscle contraction
and are believed to be the main component of the mammalian cardiac intercalated discs (see Franke et al. 2006; Pieperhoff and Franke, 2007; Pieperhoff and Franke, 2008; see also Goossens et al., 2007). Area composita structures consist of typical desmosomal in addition to typical fascia adhaerens proteins, whereas in epithelia both molecular classes show distinct and mutual exclusive localizations and both structures are also well separated.
Heart
The heart is a myogenic muscular organ found in all animals with a circulatory system , that is responsible for pumping blood throughout the blood vessels by repeated, rhythmic contractions...
muscle specific mixed type adhering junction connecting single cardiomyocytes. They are responsible for the force transmission during muscle contraction
Muscle contraction
Muscle fiber generates tension through the action of actin and myosin cross-bridge cycling. While under tension, the muscle may lengthen, shorten, or remain the same...
and are believed to be the main component of the mammalian cardiac intercalated discs (see Franke et al. 2006; Pieperhoff and Franke, 2007; Pieperhoff and Franke, 2008; see also Goossens et al., 2007). Area composita structures consist of typical desmosomal in addition to typical fascia adhaerens proteins, whereas in epithelia both molecular classes show distinct and mutual exclusive localizations and both structures are also well separated.