Anti-glomerular basement membrane antibody
Encyclopedia
Anti-glomerular basement membrane antibody (anti-GBM) is an antibody
which is found in Goodpasture's syndrome
but not found in microscopic polyangiitis
.
Some sources consider "anti-GBM disease" and "Goodpasture disease" to be synonomyous terms describing histological presentation, reserving the term "Goodpasture syndrome" for clinical presentation.
Antibody
An antibody, also known as an immunoglobulin, is a large Y-shaped protein used by the immune system to identify and neutralize foreign objects such as bacteria and viruses. The antibody recognizes a unique part of the foreign target, termed an antigen...
which is found in Goodpasture's syndrome
Goodpasture's syndrome
Goodpasture’s syndrome is a rare disease characterized by glomerulonephritis and hemorrhaging of the lungs...
but not found in microscopic polyangiitis
Microscopic polyangiitis
Microscopic polyangiitis is an ill-defined autoimmune disease characterized by pauci-immune, necrotizing, small-vessel vasculitis without clinical or pathological evidence of necrotizing granulomatous inflammation.-Presentation:Because many different organ systems may be involved, a wide range of...
.
Some sources consider "anti-GBM disease" and "Goodpasture disease" to be synonomyous terms describing histological presentation, reserving the term "Goodpasture syndrome" for clinical presentation.