Anthony John Clark
Encyclopedia
John Clark (18 September 1951 – 12 August 2004) was the head of the Roslin Institute .
English molecular biologist who was a founder of applying molecular technology to farm animals. In 1985, he began work in genetic modification (at what is now the Roslin Institute) to produce a sheep giving milk with human proteins. He was successful within five years. Tracy, the result of five year's work, produced 35g of the alpha-1-antitrypsin (used in treatment of cystic fibrosis) in each liter of her milk. During the 1990s, Clark continued to develop transgenic techniques on large animals. With his colleagues, he produced a sheep from which a prion protein gene had been removed. Clark's work set the stage for Ian Wilmut's team at Roslin to clone a sheep, Dolly (1996), the result of transplanted DNA of an adult sheep to an unfertilized egg cell.
English molecular biologist who was a founder of applying molecular technology to farm animals. In 1985, he began work in genetic modification (at what is now the Roslin Institute) to produce a sheep giving milk with human proteins. He was successful within five years. Tracy, the result of five year's work, produced 35g of the alpha-1-antitrypsin (used in treatment of cystic fibrosis) in each liter of her milk. During the 1990s, Clark continued to develop transgenic techniques on large animals. With his colleagues, he produced a sheep from which a prion protein gene had been removed. Clark's work set the stage for Ian Wilmut's team at Roslin to clone a sheep, Dolly (1996), the result of transplanted DNA of an adult sheep to an unfertilized egg cell.