Anthera Pharmaceuticals
Encyclopedia
Anthera Pharmaceuticals, Inc. is a pharmaceutical company
Pharmaceutical company
The pharmaceutical industry develops, produces, and markets drugs licensed for use as medications. Pharmaceutical companies are allowed to deal in generic and/or brand medications and medical devices...

 that specializes in developing treatments for serious cardiovascular
Cardiovascular disease
Heart disease or cardiovascular disease are the class of diseases that involve the heart or blood vessels . While the term technically refers to any disease that affects the cardiovascular system , it is usually used to refer to those related to atherosclerosis...

 and autoimmune diseases. It is headquartered in Hayward, California
Hayward, California
Hayward is a city located in the East Bay in Alameda County, California. With a population of 144,186, Hayward is the sixth largest city in the San Francisco Bay Area and the third largest in Alameda County. Hayward was ranked as the 37th most populous municipality in California. It is included in...

.

Product Candidates

Anthera has one drug in Phase III of clinical development, and two in Phase II.
  • Varespladib methyl
    Varespladib methyl
    Varespladib methyl is a secretory phospholipase A2 inhibitor under development by Anthera Pharmaceuticals as a treatment for acute coronary syndrome . Varespladib methyl is an orally bioavailable prodrug of the molecule varespladib...

    , an investigational anti-inflammatory
    Anti-inflammatory
    Anti-inflammatory refers to the property of a substance or treatment that reduces inflammation. Anti-inflammatory drugs make up about half of analgesics, remedying pain by reducing inflammation as opposed to opioids, which affect the central nervous system....

     agent for the treatment of acute coronary syndrome
    Acute coronary syndrome
    Acute coronary syndrome is usually one of three diseases involving the coronary arteries: ST elevation myocardial infarction , non ST elevation myocardial infarction , or unstable angina ....

    .
  • Blisibimod
    Blisibimod
    Blisibimod is a selective peptibody antagonist of B-cell activating factor , being developed by Anthera Pharmaceuticals as a treatment for systemic lupus erythematosus...

    , an investigational anti-BAFF
    B-cell activating factor
    B-cell activating factor also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFLSF13B gene...

     molecule for the treatment of systemic lupus erythematosus
    Systemic lupus erythematosus
    Systemic lupus erythematosus , often abbreviated to SLE or lupus, is a systemic autoimmune disease that can affect any part of the body. As occurs in other autoimmune diseases, the immune system attacks the body's cells and tissue, resulting in inflammation and tissue damage...

    .
  • Varespladib sodium, an investigational anti-inflammatory agent for the treatment of acute chest syndrome
    Acute chest syndrome
    The acute chest syndrome is a noninfectious vaso-occlusive crisis of the pulmonary vasculature commonly seen in patients with sickle cell anemia.It is characterized by a new infiltrate on a chest x-ray.-Cause:...

    .

External Links

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