Amino acid transporter
Encyclopedia
An amino acid transporter is a membrane transport protein that transports amino acid
Amino acid
Amino acids are molecules containing an amine group, a carboxylic acid group and a side-chain that varies between different amino acids. The key elements of an amino acid are carbon, hydrogen, oxygen, and nitrogen...

s. They are mainly of the solute carrier family
Solute carrier family
The solute carrier group of membrane transport proteins include over 300 members organized into 51 families. The SLC gene nomenclature system was originally proposed by the Human Genome Organization and is the basis for the official HUGO names of the genes that encode these transporters...

.

Solute carrier family examples

  • (1) high affinity glutamate and neutral amino acid transporter
    Glutamate transporter
    Excitatory amino-acid transporters , formerly known as Glutamate transporters, belong to the family of neurotransmitter transporters. They serve to terminate the excitatory neurotransmitter signal by removal of glutamate from the neuronal synapse into Glia cells.In details, the EAATs are...

  • (3) heavy subunits of heteromeric amino acid transporters
  • (7) cationic amino acid transporter/glycoprotein-associated
  • (15) proton oligopeptide cotransporter
  • (17) vesicular glutamate transporter
  • (18) vesicular amine transporter
  • (25) some mitochondrial carrier
    Mitochondrial carrier
    Mitochondrial carriers are proteins from the solute carrier family which transfers molecules across the membranes of the mitochondria.- Function :...

    s
  • (26) multifunctional anion exchanger
  • (32) vesicular inhibitory amino acid transporter
  • (36) proton-coupled amino acid transporter
  • (38) System A & N, sodium-coupled neutral amino acid transporter

VIAAT


Vesicular inhibitory amino acid transporter (VIAAT) is responsible for the storage of GABA and glycine in neuronal synaptic vesicles.

Human proteins containing this domain

ATA2; SLC32A1
SLC32A1
Vesicular inhibitory amino acid transporter is a protein that in humans is encoded by the SLC32A1 gene.-Further reading:...

; SLC36A1
SLC36A1
Proton-coupled amino acid transporter 1 is a protein that in humans is encoded by the SLC36A1 gene.-Further reading:...

; SLC36A2
SLC36A2
Solute carrier family 36, member 2 also known as SLC36A2 is a protein which in humans is encoded by the SLC36A2 gene.- Function :...

; SLC36A3; SLC36A4; SLC38A1
SLC38A1
Sodium-coupled neutral amino acid transporter 1 is a protein that in humans is encoded by the SLC38A1 gene.-Further reading:...

;
SLC38A2
SLC38A2
Sodium-coupled neutral amino acid transporter 2 is a protein that in humans is encoded by the SLC38A2 gene.-Further reading:...

; SLC38A3
SLC38A3
Sodium-coupled neutral amino acid transporter 3 is a protein that in humans is encoded by the SLC38A3 gene.-Further reading:...

; SLC38A4; SLC38A5; SLC38A6;
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