Alpha-v beta-5
Encyclopedia
αVβ5 is a type of integrin
that binds to matrix macromolecules and proteinases and thereby stimulates angiogenesis
. However, recent studies indicate that it actually inhibits angiogenesis.
Integrin
Integrins are receptors that mediate attachment between a cell and the tissues surrounding it, which may be other cells or the ECM. They also play a role in cell signaling and thereby regulate cellular shape, motility, and the cell cycle....
that binds to matrix macromolecules and proteinases and thereby stimulates angiogenesis
Angiogenesis
Angiogenesis is the physiological process involving the growth of new blood vessels from pre-existing vessels. Though there has been some debate over terminology, vasculogenesis is the term used for spontaneous blood-vessel formation, and intussusception is the term for the formation of new blood...
. However, recent studies indicate that it actually inhibits angiogenesis.