Alexander Bachmanov
Encyclopedia
Dr. Alexander Bachmanov is a scientist and geneticist
currently working at the Monell Chemical Senses Center
in Philadelphia, Pennsylvania. His research focuses on the genetics of taste
, ingestive behavior and alcohol intake. His studies are based on genetic variation
among mouse
strains; he uses mice with contrasting phenotypes for genetic analyses. The goal of these analyses is to find chromosomal locations of genes involved in taste-related behavior, with an ultimate goal to identify the molecular identity of these genes using the positional cloning approach. In addition, Dr. Bachmanov uses physiological and behavioral techniques to better understand mechanisms responsible for genetic differences in taste-related behavior.
Genetics
Genetics , a discipline of biology, is the science of genes, heredity, and variation in living organisms....
currently working at the Monell Chemical Senses Center
Monell Chemical Senses Center
The Monell Chemical Senses Center is a non-profit independent scientific institute located at the University City Science Center research campus in Philadelphia, Pennsylvania...
in Philadelphia, Pennsylvania. His research focuses on the genetics of taste
Taste
Taste is one of the traditional five senses. It refers to the ability to detect the flavor of substances such as food, certain minerals, and poisons, etc....
, ingestive behavior and alcohol intake. His studies are based on genetic variation
Genetic variation
Genetic variation, variation in alleles of genes, occurs both within and among populations. Genetic variation is important because it provides the “raw material” for natural selection. Genetic variation is brought about by mutation, a change in a chemical structure of a gene. Polyploidy is an...
among mouse
MICE
-Fiction:*Mice , alien species in The Hitchhiker's Guide to the Galaxy*The Mice -Acronyms:* "Meetings, Incentives, Conferencing, Exhibitions", facilities terminology for events...
strains; he uses mice with contrasting phenotypes for genetic analyses. The goal of these analyses is to find chromosomal locations of genes involved in taste-related behavior, with an ultimate goal to identify the molecular identity of these genes using the positional cloning approach. In addition, Dr. Bachmanov uses physiological and behavioral techniques to better understand mechanisms responsible for genetic differences in taste-related behavior.
Select publications
- Bachmanov AA, Reed DR, Tordoff MG, Price RA, Beauchamp GK (1996)Intake of ethanol, sodium chloride, sucrose, citric acid and quinine hydrochloride solutions by mice: a genetic analysis. Behavior Genetics 26:563-573.
- Bachmanov AA, Tordoff MG, Beauchamp GK (2000) Intake of umami-tasting solutions by mice: A genetic analysis. Journal of Nutrition 130: 935S-941S.
- Bachmanov AA, Li X, Reed DR, Ohmen JD, Li S, Chen Z, Tordoff MG, de Jong PJ, Wu C, West DB, Chatterjee A, Ross DA, Beauchamp GK (2001) Positional cloning of the mouse saccharin preference (Sac) locus. Chemical Senses 26: 925-933.
- Bachmanov AA, Reed DR, Li X, Li S, Beauchamp GK, Tordoff MG (2002) Voluntary ethanol consumption by mice: Genome-wide analysis of
- quantitative trait loci and their interactions in a C57BL/6ByJ x129P3/J F2 intercross. Genome Research 12: 1257-1268.
- Bachmanov AA, Beauchamp GK (2007). Taste Receptor Genes. Annual Review of Nutrition 27:389-414.