Acacetin
Encyclopedia
Acacetin is an O-methylated flavone found in Robinia pseudoacacia (black locust) and Turnera diffusa (damiana).
The enzyme apigenin 4'-O-methyltransferase
uses S-adenosyl methionine
and 5,7,4'-trihydroxyflavone (apigenin) to produce S-adenosylhomocysteine and 4'-methoxy-5,7-dihydroxyflavone (acacetin).
The enzyme apigenin 4'-O-methyltransferase
Apigenin 4'-O-methyltransferase
In enzymology, an apigenin 4'-O-methyltransferase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are S-adenosyl methionine and 5,7,4'-trihydroxyflavone , whereas its two products are S-adenosylhomocysteine and 4'-methoxy-5,7-dihydroxyflavone .This enzyme...
uses S-adenosyl methionine
S-Adenosyl methionine
S-Adenosyl methionine is a common cosubstrate involved in methyl group transfers. SAM was first discovered in Italy by G. L. Cantoni in 1952. It is made from adenosine triphosphate and methionine by methionine adenosyltransferase . Transmethylation, transsulfuration, and aminopropylation are the...
and 5,7,4'-trihydroxyflavone (apigenin) to produce S-adenosylhomocysteine and 4'-methoxy-5,7-dihydroxyflavone (acacetin).