
Abarelix
    
    Encyclopedia
    
        Abarelix is an injectable gonadotropin-releasing hormone
antagonist (GnRH antagonist
). It is primarily used in oncology
to reduce the amount of testosterone
made in patients with advanced symptomatic prostate cancer
for which no other treatment options are available. It belongs to the family of drugs called Gonadotropin-releasing hormone antagonist
s.
It is marketed by Speciality European Pharma as Plenaxis. Plenaxis has received marketing authorisation in Germany.
Gonadotropin-releasing hormone
Gonadotropin-releasing hormone , also known as Luteinizing-hormone-releasing hormone  and luliberin, is a tropic peptide hormone responsible for the release of follicle-stimulating hormone  and luteinizing hormone  from the anterior pituitary. GnRH is synthesized and released from neurons within...
antagonist (GnRH antagonist
Gonadotropin-releasing hormone antagonist
Gonadotrophin-releasing hormone  antagonists  are a class of compounds that are similar in structure to natural GnRH  but that have an antagonistic effect. GnRH antagonists are peptide molecules that are made up multiple, often synthetically produced amino acids...
). It is primarily used in oncology
Oncology
Oncology  is a branch of medicine that deals with cancer...
to reduce the amount of testosterone
Testosterone
Testosterone is a steroid hormone from the androgen group and is found in mammals, reptiles, birds, and other vertebrates.   In mammals, testosterone is primarily secreted in the testes of males and the ovaries of females, although small amounts are also secreted by the adrenal glands...
made in patients with advanced symptomatic prostate cancer
Prostate cancer
Prostate cancer is a form of cancer that develops in the prostate, a gland in the male reproductive system. Most prostate cancers are slow growing; however, there are cases of aggressive prostate cancers.  The cancer cells may metastasize  from the prostate to other parts of the body, particularly...
for which no other treatment options are available. It belongs to the family of drugs called Gonadotropin-releasing hormone antagonist
Gonadotropin-releasing hormone antagonist
Gonadotrophin-releasing hormone  antagonists  are a class of compounds that are similar in structure to natural GnRH  but that have an antagonistic effect. GnRH antagonists are peptide molecules that are made up multiple, often synthetically produced amino acids...
s.
It is marketed by Speciality European Pharma as Plenaxis. Plenaxis has received marketing authorisation in Germany.


