ATPase, H+/K+ transporting, nongastric, alpha polypeptide (also known as ATP12A) is a protein

Protein

Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...

 that in humans is encoded by the ATP12A gene

Gene

A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

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Function

The protein encoded by this gene belongs to the family of P-type

P-type ATPase

The P-type ATPases, also known as E1-E2 ATPases, are a large group of evolutionarily related ion pumps that are found in bacteria, archaea and eukaryotes. They are α-helical bundle primary transporters referred to as P-type ATPases because they catalyze auto- phosphorylation of a key conserved...

 cation transport ATPase

ATPase

ATPases are a class of enzymes that catalyze the decomposition of adenosine triphosphate into adenosine diphosphate and a free phosphate ion. This dephosphorylation reaction releases energy, which the enzyme harnesses to drive other chemical reactions that would not otherwise occur...

s. This gene encodes a catalytic subunit of the ouabain

Ouabain

Ouabain which is also named g-strophanthin, is a poisonous cardiac glycoside.-Sources:Ouabain is found in the ripe seeds of African plants Strophanthus gratus and the bark of Acokanthera ouabaio.-Function:...

-sensitive H⁺/K⁺ -ATPase that catalyzes the hydrolysis of ATP coupled with the exchange of H⁺ and K⁺ ions across the plasma membrane. It is also responsible for potassium absorption in various tissues.

Further reading