ATN1
Encyclopedia
ATN1 is a protein found in nervous tissue
.
It is associated with a form of trinucleotide repeat disorder known as "dentatorubral-pallidoluysian atrophy
" or "dentatorubropallidoluysian atrophy".
with BAIAP2
, MAGI2
, WWP2
, RERE
and MAGI1
.
Nervous tissue
Nervous tissue is one of four major classes of vertebrate tissue.Nervous tissue is the main component of the nervous system - the brain, spinal cord, and nerves-which regulates and controls body functions...
.
It is associated with a form of trinucleotide repeat disorder known as "dentatorubral-pallidoluysian atrophy
Dentatorubral-pallidoluysian atrophy
Dentatorubral-pallidoluysian atrophy is an autosomal dominant spinocerebellar degeneration caused by an expansion of a CAG repeat encoding a polyglutamine tract in the atrophin-1 protein. It is also known as Haw River Syndrome and Naito-Oyanagi disease. Although this condition was perhaps first...
" or "dentatorubropallidoluysian atrophy".
Interactions
ATN1 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with BAIAP2
BAIAP2
Brain-specific angiogenesis inhibitor 1-associated protein 2 is a protein that in humans is encoded by the BAIAP2 gene.-Interactions:BAIAP2 has been shown to interact with WASF1, EPS8, SHANK1, RAC1, WASF2, ATN1 and CDC42.-Further reading:...
, MAGI2
MAGI2
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 also known as membrane-associated guanylate kinase inverted 2 and atrophin-1-interacting protein 1 is an enzyme that in humans is encoded by the MAGI2 gene.- Function :The protein encoded by this gene interacts with...
, WWP2
WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2 also known as atrophin-1-interacting protein 2 or WW domain-containing protein 2 is an enzyme that in humans is encoded by the WWP2 gene.- Function :...
, RERE
RERE
Arginine-glutamic acid dipeptide repeats protein is a protein that in humans is encoded by the RERE gene.-Further reading:...
and MAGI1
MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 is an enzyme that in humans is encoded by the MAGI1 gene.-Interactions:...
.