ATC code M04
Encyclopedia
M04AA Preparations inhibiting uric acidUric acidUric acid is a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen with the formula C5H4N4O3. It forms ions and salts known as urates and acid urates such as ammonium acid urate. Uric acid is created when the body breaks down purine nucleotides. High blood concentrations of uric acid...
production
- M04AA01 AllopurinolAllopurinolAllopurinol is a drug used primarily to treat hyperuricemia and its complications, including chronic gout.- Mechanism of action :...
- M04AA02 TisopurineTisopurineTisopurine is a drug used in the treatment of gout....
- M04AA03 FebuxostatFebuxostatFebuxostat is a urate lowering drug, an inhibitor of xanthine oxidase that is indicated for use in the treatment of hyperuricemia and gout....
- M04AA51 Allopurinol, combinations
M04AB Preparations increasing uric acid excretionUricosuricUricosuric medications are substances that increase the excretion of uric acid in the urine, thus reducing the concentration of uric acid in blood plasma. In general, this effect is achieved by action on the proximal tubule...
- M04AB01 ProbenecidProbenecidProbenecid is a uricosuric drug that increases uric acid excretion in the urine. It is primarily used in treating gout and hyperuricemia.Probenecid was developed as an alternative to caronamide...
- M04AB02 SulfinpyrazoneSulfinpyrazoneSulfinpyrazone is a uricosuric medication used to treat gout. It also sometimes is used to reduce platelet aggregation by inhibiting degranulation of platelets which reduces the release of ADP and thromboxane....
- M04AB03 BenzbromaroneBenzbromaroneBenzbromarone is a uricosuric agent used in the treatment of gout, especially when allopurinol, a first-line treatment, fails or produces intolerable adverse effects...
- M04AB04 IsobromindioneIsobromindioneIsobromindione is a drug used in the treatment of gout....
M04AC Preparations with no effect on uric acid metabolism
- M04AC01 ColchicineColchicineColchicine is a medication used for gout. It is a toxic natural product and secondary metabolite, originally extracted from plants of the genus Colchicum...
- M04AC02 CinchophenCinchophenCinchophen is an analgesic drug that was introduced in 1910 and frequently used to treat gout...
M04AX Other antigout preparations
- M04AX01 Urate oxidaseUrate oxidaseThe enzyme urate oxidase , or uricase or factor-independent urate hydroxylase, catalyzes the oxidation of uric acid to 5-hydroxyisourate:-Structure:...
- M04AX02 PegloticasePegloticasePegloticase is a drug for the treatment of severe, treatment-refractory, chronic gout, developed by Savient Pharmaceuticals...