ATC code C02
Encyclopedia

C02AA Rauwolfia
Rauwolfia
Rauvolfia is a genus of evergreen trees and shrubs in the dogbane family, Apocynaceae. The genus is named to honor Leonhard Rauwolf. The approximately 85 species in the genus can mainly be found in tropical regions...

 alkaloid
Alkaloid
Alkaloids are a group of naturally occurring chemical compounds that contain mostly basic nitrogen atoms. This group also includes some related compounds with neutral and even weakly acidic properties. Also some synthetic compounds of similar structure are attributed to alkaloids...

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C02AA01 Rescinnamine
Rescinnamine
Rescinnamine is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug.It is an alkaloid obtained from Rauwolfia serpentina and other species of Rauwolfia....

C02AA02 Reserpine
Reserpine
Reserpine is an indole alkaloid antipsychotic and antihypertensive drug that has been used for the control of high blood pressure and for the relief of psychotic symptoms, although because of the development of better drugs for these purposes and because of its numerous side-effects, it is rarely...

C02AA03 Combinations of rauwolfia alkaloids
C02AA04 Rauwolfia alkaloids, whole root
Root
In vascular plants, the root is the organ of a plant that typically lies below the surface of the soil. This is not always the case, however, since a root can also be aerial or aerating . Furthermore, a stem normally occurring below ground is not exceptional either...

C02AA05 Deserpidine
Deserpidine
Deserpidine is an antihypertensive drug related to reserpine.-References:...

C02AA06 Methoserpidine
Methoserpidine
Methoserpidine is an antihypertensive drug related to reserpine....

C02AA07 Bietaserpine
Bietaserpine
Bietaserpine , or 1-diaminoethylreserpine, is a derivative of reserpine used as an antihypertensive agent....

C02AA52 Reserpine, combinations
C02AA53 Combinations of rauwolfia alkoloids, combinations
C02AA57 Bietaserpine, combinations

C02AB Methyldopa
Methyldopa
Methyldopa is an alpha-adrenergic agonist psychoactive drug used as a sympatholytic or antihypertensive. Its use is now mostly deprecated following the introduction of alternative safer classes of agents...

C02AB01 Methyldopa
Methyldopa
Methyldopa is an alpha-adrenergic agonist psychoactive drug used as a sympatholytic or antihypertensive. Its use is now mostly deprecated following the introduction of alternative safer classes of agents...

 (levorotatory)
C02AB02 Methyldopa (racemic
Racemic
In chemistry, a racemic mixture, or racemate , is one that has equal amounts of left- and right-handed enantiomers of a chiral molecule. The first known racemic mixture was "racemic acid", which Louis Pasteur found to be a mixture of the two enantiomeric isomers of tartaric acid.- Nomenclature :A...

)

C02AC Imidazoline
Imidazoline
Imidazoline is a nitrogen-containing heterocycle with formula C3H6N2, derived from imidazole. The ring contains an imine bond, and the carbons at the 4 and 5 positions are singly bonded, rather than doubly bonded for the case of imidazole...

 receptor agonists

C02AC01 Clonidine
Clonidine
Clonidine is a sympatholytic medication used to treat medical conditions, such as high blood pressure, some pain conditions, ADHD and anxiety/panic disorder...

C02AC02 Guanfacine
Guanfacine
Guanfacine is a sympatholytic. It is an agonist of the α2A subtype of norepinephrine receptors. These receptors are concentrated heavily in the prefrontal cortex and the locus coeruleus, with the potential to improve attention abilities via modulating post-synaptic α2A receptors in the prefrontal...

C02AC04 Tolonidine
Tolonidine
Tolonidine is an antihypertensive....

C02AC05 Moxonidine
Moxonidine
Moxonidine is a new generation centrally acting antihypertensive drug licensed for the treatment of mild to moderate essential hypertension. It may have a role when thiazides, beta-blockers, ACE inhibitors and calcium channel blockers are not appropriate or have failed to control blood pressure...

C02AC06 Rilmenidine
Rilmenidine
Rilmenidine is a prescription medication for the treatment of hypertension. It is marketed under the brand names HYPERIUM and Tenaxum.- Form and composition :...


C02CA Alpha-adrenoreceptor antagonists

C02CA01 Prazosin
Prazosin
Prazosin, trade names Minipress, Vasoflex, Pressin and Hypovase, is a sympatholytic drug used to treat high blood pressure and Anxiety, PTSD and Panic Disorder. It belongs to the class of alpha-adrenergic blockers. Specifically, prazosin is selective for the alpha-1 receptors on vascular smooth...

C02CA02 Indoramin
Indoramin
Indoramin is a piperidine antiadrenergic agent.It is an alpha-1 selective adrenoceptor antagonist. with direct myocardial depression action,therefore,it results in no reflex tachycardiaIt is commonly synthesized from tryptophol...

C02CA03 Trimazosin
Trimazosin
Trimazosin is a sympatholytic drug.It is an alpha blocker.Hess, H. J.; 1972, .-References:...

C02CA04 Doxazosin
Doxazosin
Doxazosin mesylate, a quinazoline compound sold by Pfizer under the brand names Cardura and Carduran, is an α1a-selective alpha blocker used to treat high blood pressure and urinary retention associated with benign prostatic hyperplasia ....

C02CA06 Urapidil
Urapidil
Urapidil is a sympatholytic antihypertensive drug. It acts as an α1-adrenoceptor antagonist and as an 5-HT1A receptor agonist Although an initial report suggested that urapidil was also an α2-adrenoceptor agonist, this was not substantiated in later studies that demonstrated it was devoid of...


C02CC Guanidine
Guanidine
Guanidine is a crystalline compound of strong alkalinity formed by the oxidation of guanine. It is used in the manufacture of plastics and explosives. It is found in urine as a normal product of protein metabolism. The molecule was first synthesized in 1861 by the oxidative degradation of an...

 derivatives

C02CC01 Betanidine
Betanidine
Betanidine is a sympatholytic drug....

C02CC02 Guanethidine
Guanethidine
Guanethidine is an antihypertensive drug that reduces the release of catecholamines, such as norepinephrine. Guanethidine is transported across the sympathetic nerve membrane by the same mechanism that transports norepinephrine itself , and uptake is essential for the drug's action...

C02CC03 Guanoxan
Guanoxan
Guanoxan is a sympatholytic drug....

C02CC04 Debrisoquine
Debrisoquine
Debrisoquine is a derivative of guanidine. It is an antihypertensive drug similar to guanethidine. Debrisoquine is frequently used for phenotyping the CYP2D6 enzyme, a drug metabolizing enzyme....

C02CC05 Guanoclor
Guanoclor
Guanoclor is a sympatholytic drug....

C02CC06 Guanazodine
Guanazodine
Guanazodine is a sympatholytic drug....

C02CC07 Guanoxabenz
Guanoxabenz
Guanoxabenz is a metabolite of guanabenz....


C02DB Hydrazinophthalazine derivatives

C02DB01 Dihydralazine
Dihydralazine
Dihydralazine is an antihypertensive of the hydrazine chemical class....

C02DB02 Hydralazine
Hydralazine
Hydralazine is a direct-acting smooth muscle relaxant used to treat hypertension by acting as a vasodilator primarily in arteries and arterioles...

C02DB03 Endralazine
Endralazine
Endralazine is an antihypertensive of the hydrazine chemical class.- See also :* Cadralazine* Dihydralazine* Hydralazine...

C02DB04 Cadralazine
Cadralazine
Cadralazine is an antihypertensive of the hydrazine chemical class.- References :...


C02KX Other antihypertensives

C02KX01 Bosentan
Bosentan
Bosentan is a dual endothelin receptor antagonist used in the treatment of pulmonary artery hypertension . It is licensed in the United States, the European Union and other countries by Actelion Pharmaceuticals for the management of PAH under the trade name Tracleer.-Mechanism of action:Bosentan is...

C02KX02 Ambrisentan
Ambrisentan
Ambrisentan is a drug indicated for use in the treatment of pulmonary hypertension.It functions as an endothelin receptor antagonist, and is selective for the type A endothelin receptor ....

C02KX03 Sitaxentan

C02LA Rauwolfia alkaloids and diuretics in combination

C02LA01 Reserpine and diuretics
C02LA02 Rescinnamine and diuretics
C02LA03 Deserpidine and diuretics
C02LA04 Methoserpidine and diuretics
C02LA07 Bietaserpine and diuretics
C02LA08 Rauwolfia alkaloids, whole root and diuretics
C02LA09 Syrosingopine and diuretics
C02LA50 Combinations of rauwolfia alkaloids and diuretics including other combinations
C02LA51 Reserpine and diuretics, combinations with other drugs
C02LA52 Rescinnamine and diuretics, combinations with other drugs
C02LA71 Reserpine and diuretics, combinations with psycholeptic
Psycholeptic
In pharmacology, a psycholeptic is a medication which produces a calming effect upon the patient.The psycholeptics are classified under N05 in the Anatomical Therapeutic Chemical Classification System.-External links:...

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C02LB Methyldopa and diuretics in combination

C02LB01 Methyldopa (levorotatory) and diuretics

C02LC Imidazoline receptor agonists in combination with diuretics

C02LC01 Clonidine and diuretics
C02LC05 Moxonidine and diuretics
C02LC51 Clonidine and diuretics, combinations with other drugs

C02LE Alpha-adrenoreceptor antagonists and diuretics

C02LE01 Prazosin and diuretics

C02LG Hydrazinophthalazine derivatives and diuretics

C02LG01 Dihydralazine and diuretics
C02LG02 Hydralazine and diuretics
C02LG03 Picodralazine and diuretics
C02LG51 Dihydralazine and diuretics, combinations with other drugs
C02LG73 Picodralazine and diuretics, combinations with psycholeptics

C02LK Alkaloids, excluding rauwolfia, in combination with diuretics

C02LK01 Veratrum and diuretics
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