ARHGEF12
Encyclopedia
Rho guanine nucleotide exchange factor 12 is a protein
that in humans is encoded by the ARHGEF12 gene
.
with Insulin-like growth factor 1 receptor, GNA13
, PLXNB1
, GNA12
, TEC
and RHOA
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the ARHGEF12 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
ARHGEF12 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with Insulin-like growth factor 1 receptor, GNA13
GNA13
Guanine nucleotide-binding protein subunit alpha-13 is a protein that in humans is encoded by the GNA13 gene.-Interactions:GNA13 has been shown to interact with ARHGEF1, AKAP3, RIC8A, Radixin and ARHGEF12.-Further reading:...
, PLXNB1
PLXNB1
Plexin B1 is a protein of the plexin family that in humans is encoded by the PLXNB1 gene.-Interactions:PLXNB1 has been shown to interact with ARHGEF12, Rnd1 and ARHGEF11.-Further reading:...
, GNA12
GNA12
Guanine nucleotide-binding protein subunit alpha-12 is a protein that in humans is encoded by the GNA12 gene.-Interactions:GNA12 has been shown to interact with ARHGEF1, PPP5C, ARHGEF12, Heat shock protein 90kDa alpha , member A1 and TEC....
, TEC
TEC (gene)
Tyrosine-protein kinase Tec is an enzyme that in humans is encoded by the TEC gene.-Interactions:TEC has been shown to interact with GNA12, Janus kinase 2, CD117, Suppressor of cytokine signaling 1, ARHGEF12 and DOK1.-Further reading:...
and RHOA
RHOA
Ras homolog gene family, member A is a small GTPase protein known to regulate the actin cytoskeleton in the formation of stress fibers. In humans, it is encoded by the gene RHOA....
.