ACVR2A
Encyclopedia
Activin receptor type-2A is a protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...

 that in humans is encoded by the ACVR2A gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

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ACVR2A is an activin type 2 receptor.

Interactions

ACVR2A has been shown to interact
Protein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...

 with INHBA
INHBA
Inhibin, beta A, also known as INHBA, is a protein which in humans is encoded by the INHBA gene. INHBA is a subunit of both activin and inhibin, two closely related glycoproteins with opposing biological effects.- Function :...

, SYNJ2BP
SYNJ2BP
Synaptojanin-2-binding protein is a protein that in humans is encoded by the SYNJ2BP gene.-Interactions:SYNJ2BP has been shown to interact with LRP2, ACVR2B, ACVR2A and LRP1.-Further reading:...

 and ACVR1B
ACVR1B
Activin receptor type-1B is a protein that in humans is encoded by the ACVR1B gene.ACVR1B or ALK-4 acts as a transducer of activin or activin like ligands signals. Activin binds to either ACVR2A or ACVR2B and then forms a complex with ACVR1B. These go on to recruit the R-SMADs SMAD2 or SMAD3...

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Further reading

The source of this article is wikipedia, the free encyclopedia.  The text of this article is licensed under the GFDL.
 
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