ACER1
Encyclopedia
Alkaline ceramidase 1 also known as ACER1 is a ceramidase
enzyme which in humans is encoded by the ACER1 gene
.
by controlling the generation of sphingosine
(SPH) and sphingosine-1-phosphate
(S1P).
Ceramidase
Ceramidase is an enzyme which cleaves fatty acids from ceramide, producing sphingosine which in turn is phosphorylated by a sphingosine kinase to form sphingosine-1-phosphate .- Function :...
enzyme which in humans is encoded by the ACER1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Function
ACER1 mediates cellular differentiationCellular differentiation
In developmental biology, cellular differentiation is the process by which a less specialized cell becomes a more specialized cell type. Differentiation occurs numerous times during the development of a multicellular organism as the organism changes from a simple zygote to a complex system of...
by controlling the generation of sphingosine
Sphingosine
Sphingosine is an 18-carbon amino alcohol with an unsaturated hydrocarbon chain, which forms a primary part of sphingolipids, a class of cell membrane lipids that include sphingomyelin, an important phospholipid.-Functions:...
(SPH) and sphingosine-1-phosphate
Sphingosine-1-phosphate
Sphingosine-1-phosphate is a signaling sphingolipid. It is also referred to as a bioactive lipid mediator. Sphingolipids at large form a class of lipids characterized by a particular aliphatic aminoalcohol, which is sphingosine.-Production:...
(S1P).