7-alpha-hydroxycholesterol
Encyclopedia
7α-Hydroxycholesterol is a precursor of bile acid
s, created by cholesterol 7 alpha-hydroxylase
. It is the rate-determining step
.
Bile acid
Bile acids are steroid acids found predominantly in the bile of mammals. Bile salts are bile acids compounded with a cation, usually sodium. In humans, the salts of taurocholic acid and glycocholic acid represent approximately eighty percent of all bile salts. The two major bile acids are cholic...
s, created by cholesterol 7 alpha-hydroxylase
Cholesterol 7 alpha-hydroxylase
Cholesterol 7 alpha-hydroxylase also known as cholesterol 7-alpha-monooxygenase or cytochrome P450 7A1 is an enzyme that in humans is encoded by the CYP7A1 gene.- Function :...
. It is the rate-determining step
Rate-determining step
The rate-determining step is a chemistry term for the slowest step in a chemical reaction. The rate-determining step is often compared to the neck of a funnel; the rate at which water flows through the funnel is determined by the width of the neck, not by the speed at which water is poured in. In...
.