4-Hydroxy-3-nitrobenzenearsonic acid
Encyclopedia
4-Hydroxy-3-nitrobenzenearsonic acid is an organic compound
Organic compound
An organic compound is any member of a large class of gaseous, liquid, or solid chemical compounds whose molecules contain carbon. For historical reasons discussed below, a few types of carbon-containing compounds such as carbides, carbonates, simple oxides of carbon, and cyanides, as well as the...

 that is widely used agriculturally as a chicken-feed additive. The molecule is a derivative of phenylarsonic acid
Phenylarsonic acid
Phenylarsonic acid is the chemical compound with the formula C6H5AsO2, commonly abbreviated PhAsO3H2. This colourless solid is an organic derivative of arsenic acid, AsO3, where one OH group has been replaced by a phenyl group. The compound is a buffering agent and a precursor to other...

 (C6H5As(O)(OH)2). This organoarsenic compound
Organoarsenic compound
Organoarsenic chemistry is the chemistry of compounds containing a chemical bond between arsenic and carbon. A few organoarsenic compounds, also called "organoarsenicals," are produced industrially with uses as insecticides, herbicides, and fungicides. In general these applications are declining in...

, usually under the tradename Roxarsone, has attracted attention as a source of arsenic contamination of the food chain. Approximately 1 million kilograms of this compound was produced in 2006 in the US. This compound was first reported in a 1923 British patent which describes the nitration and diazotization of arsanilic acid. This compound when blended with calcite powder, is widely used to make feed premixes in the poultry industry and is usually available in 5%, 20% and 50% concentrations.

In June 2011, the FDA has given Pfizer 30 days to discontinue selling this product; the FDA's findings indicated high levels of arsenic in these chickens consuming the arsonic acid.

External links

  • No Arsenic In Pardoned Turkeys, But It Might Be In Yours at NPR
    NPR
    NPR, formerly National Public Radio, is a privately and publicly funded non-profit membership media organization that serves as a national syndicator to a network of 900 public radio stations in the United States. NPR was created in 1970, following congressional passage of the Public Broadcasting...

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