3-Methoxyphencyclidine (3-MeO-PCP) is a dissociative

Dissociative drug

Dissociatives are a class of psychoactive drugs which are said to reduce or block signals to the conscious mind from other parts of the brain...

 anesthetic

Anesthesia

Anesthesia, or anaesthesia , traditionally meant the condition of having sensation blocked or temporarily taken away...

 drug with hallucinogenic and sedative

Sedative

A sedative or tranquilizer is a substance that induces sedation by reducing irritability or excitement....

 effects. It is around the same potency as phencyclidine

Phencyclidine

Phencyclidine , commonly initialized as PCP and known colloquially as angel dust, is a recreational dissociative drug...

, but has slightly different effects due to its altered binding profile at various targets, particularly being somewhat more potent as an NMDA antagonist while having around the same potency as a dopamine reuptake inhibitor

Dopamine reuptake inhibitor

A dopamine reuptake inhibitor is a type of drug that acts as a reuptake inhibitor for the neurotransmitter dopamine by blocking the action of the dopamine transporter...

.

The corresponding 4-methoxy derivative 4-MeO-PCP

4-MeO-PCP

4-Methoxyphencyclidine is a dissociative anesthetic drug with hallucinogenic and sedative effects. It is around the same potency as ketamine, but has slightly different effects due to its altered binding profile at various targets, particularly being somewhat more potent as an NMDA antagonist...

 is also known, but is around 10 times less potent by weight than the 3-methoxy isomer, making it around the same potency as ketamine

Ketamine

Ketamine is a drug used in human and veterinary medicine. Its hydrochloride salt is sold as Ketanest, Ketaset, and Ketalar. Pharmacologically, ketamine is classified as an NMDA receptor antagonist...

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