3-Deoxy-D-manno-oct-2-ulosonic acid
Encyclopedia
3-Deoxy-D-manno-oct-2-ulosonic acid or KDO is an ulosonic acid
of a 2-ketooctose
which is used by bacteria
in the synthesis of lipopolysaccharide
s. The D-manno prefix indicates that four chiral centers have the same configuration as D-mannose
.
Ulosonic acid
An ulosonic acid is a sugar acid obtained by the oxidation of the 1-hydroxyl group of a ketose to a carboxylic acid, creating an alpha-keto acid. An example of an ulosonic acid is ketodeoxyoctulosonic acid....
of a 2-ketooctose
Octose
An octose is a monosaccharide with eight carbons....
which is used by bacteria
Bacteria
Bacteria are a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria have a wide range of shapes, ranging from spheres to rods and spirals...
in the synthesis of lipopolysaccharide
Lipopolysaccharide
Lipopolysaccharides , also known as lipoglycans, are large molecules consisting of a lipid and a polysaccharide joined by a covalent bond; they are found in the outer membrane of Gram-negative bacteria, act as endotoxins and elicit strong immune responses in animals.-Functions:LPS is the major...
s. The D-manno prefix indicates that four chiral centers have the same configuration as D-mannose
Mannose
Mannose is a sugar monomer of the aldohexose series of carbohydrates. Mannose is a C-2 epimer of glucose. It is not part of human metabolism, but is a component of microbial cell walls, and is therefore a target of the immune system and also of antibiotics....
.