3,4-Dimethylamphetamine
Encyclopedia
Xylopropamine also known as 3,4-dimethylamphetamine, is a stimulant
drug
of the phenethylamine
and amphetamine
classes which was developed and marketed as an appetite suppressant in the 1950s.
Xylopropamine was briefly sold as the sulfate
salt
, but it was not widely marketed. Other related amphetamine derivatives such as 2,4-dimethylamphetamine were also investigated for the same purpose, however these drugs had negative side effects such as high blood pressure and were not very successful, mainly due to the introduction of alternative drugs like phentermine
which had similar efficacy but fewer side effects.
Xylopropamine was also reported as having analgesic
and anti-inflammatory
effects but its side effect profile resulted in it never being further developed for these applications.
Stimulant
Stimulants are psychoactive drugs which induce temporary improvements in either mental or physical function or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others...
drug
Drug
A drug, broadly speaking, is any substance that, when absorbed into the body of a living organism, alters normal bodily function. There is no single, precise definition, as there are different meanings in drug control law, government regulations, medicine, and colloquial usage.In pharmacology, a...
of the phenethylamine
Substituted phenethylamine
The substituted phenethylamines are chemical compounds with the 2-phenethylamine chemical structure modified at the phenyl ring, sidechain, and/or amino group. Some of them are psychoactive drugs, including stimulants, psychedelics, opioids, and entactogens, which exert their effects primarily...
and amphetamine
Substituted amphetamine
Substituted amphetamines are a chemical class of stimulants, entactogens, hallucinogens, and other drugs. They feature a phenethylamine core with a methyl group attached to the alpha carbon resulting in amphetamine, along with additional substitutions...
classes which was developed and marketed as an appetite suppressant in the 1950s.
Xylopropamine was briefly sold as the sulfate
Sulfate
In inorganic chemistry, a sulfate is a salt of sulfuric acid.-Chemical properties:...
salt
Salt
In chemistry, salts are ionic compounds that result from the neutralization reaction of an acid and a base. They are composed of cations and anions so that the product is electrically neutral...
, but it was not widely marketed. Other related amphetamine derivatives such as 2,4-dimethylamphetamine were also investigated for the same purpose, however these drugs had negative side effects such as high blood pressure and were not very successful, mainly due to the introduction of alternative drugs like phentermine
Phentermine
Phentermine, a contraction of "phenyl-tertiary-butylamine", is a psychostimulant drug of the phenethylamine class, chemically related to amphetamine. It is used medically as an appetite suppressant....
which had similar efficacy but fewer side effects.
Xylopropamine was also reported as having analgesic
Analgesic
An analgesic is any member of the group of drugs used to relieve pain . The word analgesic derives from Greek an- and algos ....
and anti-inflammatory
Anti-inflammatory
Anti-inflammatory refers to the property of a substance or treatment that reduces inflammation. Anti-inflammatory drugs make up about half of analgesics, remedying pain by reducing inflammation as opposed to opioids, which affect the central nervous system....
effects but its side effect profile resulted in it never being further developed for these applications.
See also
- MethamphetamineMethamphetamineMethamphetamine is a psychostimulant of the phenethylamine and amphetamine class of psychoactive drugs...
- DimethylamphetamineDimethylamphetamineDimethylamphetamine , also referred to as dimetamfetamine and N,N-dimethylamphetamine, is a stimulant drug of the phenethylamine and amphetamine chemical classes. Dimethylamphetamine has weaker stimulant effects than amphetamine or methamphetamine and is considerably less addictive and less...
- 3,4-Dimethylmethcathinone3,4-Dimethylmethcathinone3,4-Dimethylmethcathinone is a stimulant drug first reported in 2010 as a designer drug analogue of mephedrone, apparently produced in response to the banning of mephedrone, following its widespread abuse in many countries in Europe and around the world.-See also:* Substituted cathinone*...
- 4-Methylamphetamine4-Methylamphetamine4-Methylamphetamine is a stimulant and anorectic drug of the phenethylamine and amphetamine chemical classes....
- 4-Methylmethamphetamine4-Methylmethamphetamine4-Methylmethamphetamine is a putative stimulant and entactogen drug of the amphetamine class. It is the β-deketo analogue of mephedrone.- See also :* 4-Methylamphetamine * 4-Methylmethcathinone * 3-Methoxymethamphetamine...
- IndanylaminopropaneIndanylaminopropaneIndanylaminopropane , sometimes incorrectly referred to as indanylamphetamine, is an entactogen and psychedelic drug of the phenethylamine and amphetamine classes...