12S ribosomal RNA
Encyclopedia
Mitochondrially encoded 12S RNA (often abbreviated as 12S) is a 959 nt long mitochondrial
ribosomal RNA (rRNA
). In humans, 12S is encoded by the MTRNR1 gene
.
All animal mitochondria genomes contain 37 genes, 2 rRNA, 22 tRNA and 13 mRNA. These are very useful in phylogenetic studies, in particular the 12S and 16S rRNAs.
Mutations in the MTRNR1 gene may be associated with hearing loss.
Mitochondrion
In cell biology, a mitochondrion is a membrane-enclosed organelle found in most eukaryotic cells. These organelles range from 0.5 to 1.0 micrometers in diameter...
ribosomal RNA (rRNA
Ribosomal RNA
Ribosomal ribonucleic acid is the RNA component of the ribosome, the enzyme that is the site of protein synthesis in all living cells. Ribosomal RNA provides a mechanism for decoding mRNA into amino acids and interacts with tRNAs during translation by providing peptidyl transferase activity...
). In humans, 12S is encoded by the MTRNR1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
All animal mitochondria genomes contain 37 genes, 2 rRNA, 22 tRNA and 13 mRNA. These are very useful in phylogenetic studies, in particular the 12S and 16S rRNAs.
Mutations in the MTRNR1 gene may be associated with hearing loss.