Setback
WordNet
noun
(1) An unfortunate happening that hinders or impedes; something that is thwarting or frustrating
WiktionaryText
Noun
setback
- An obstacle, delay, or disadvantage.
- After some initial setbacks, the expedition went safely on its way.
- The required distance between a structure and a road.
- (possibly archaic) A backset; a countercurrent; an eddy.
- A backset; a check; a repulse; a ; a relapse.