Isolation
WordNet
noun
(1) The act of isolating something; setting something apart from others
(2) A country's withdrawal from international politics
"He opposed a policy of American isolation"
(3) A feeling of being disliked and alone
(4) (psychiatry) a defense mechanism in which memory of an unacceptable act or impulse is separated from the emotion originally associated with it
(5) A state of separation between persons or groups