Tilden's Extract
Encyclopedia
Tilden’s Extract was a 19th century medicinal cannabis
Medical cannabis
Medical cannabis refers to the use of parts of the herb cannabis as a physician-recommended form of medicine or herbal therapy, or to synthetic forms of specific cannabinoids such as THC as a physician-recommended form of medicine...

 extract, first formulated by James Edward Smith
James Edward Smith
Sir James Edward Smith was an English botanist and founder of the Linnean Society.Smith was born in Norwich in 1759, the son of a wealthy wool merchant. He displayed a precocious interest in the natural world...

 of Edinburgh. In the United States
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...

, the laboratory of Tilden & Co. manufactured and sold the extract under its own name, advertising the drug as:

Phrenic, anæsthetic, anti-spasmodic and hypnotic. Unlike opium
Opium
Opium is the dried latex obtained from the opium poppy . Opium contains up to 12% morphine, an alkaloid, which is frequently processed chemically to produce heroin for the illegal drug trade. The latex also includes codeine and non-narcotic alkaloids such as papaverine, thebaine and noscapine...

, it does not constipate the bowels, lessen the appetite, create nausea
Nausea
Nausea , is a sensation of unease and discomfort in the upper stomach with an involuntary urge to vomit. It often, but not always, precedes vomiting...

, produce dryness of the tongue, check pulmonary secretions or produce headache. Used with success in hysteria
Hysteria
Hysteria, in its colloquial use, describes unmanageable emotional excesses. People who are "hysterical" often lose self-control due to an overwhelming fear that may be caused by multiple events in one's past that involved some sort of severe conflict; the fear can be centered on a body part, or,...

, chorea, gout
Gout
Gout is a medical condition usually characterized by recurrent attacks of acute inflammatory arthritis—a red, tender, hot, swollen joint. The metatarsal-phalangeal joint at the base of the big toe is the most commonly affected . However, it may also present as tophi, kidney stones, or urate...

, neuralgia
Neuralgia
Neuralgia is pain in one or more nerves that occurs without stimulation of pain receptor cells. Neuralgia pain is produced by a change in neurological structure or function rather than by the excitation of pain receptors that causes nociceptive pain. Neuralgia falls into two categories: central...

, acute and sub-acute rheumatism
Rheumatism
Rheumatism or rheumatic disorder is a non-specific term for medical problems affecting the joints and connective tissue. The study of, and therapeutic interventions in, such disorders is called rheumatology.-Terminology:...

, tetanus
Tetanus
Tetanus is a medical condition characterized by a prolonged contraction of skeletal muscle fibers. The primary symptoms are caused by tetanospasmin, a neurotoxin produced by the Gram-positive, rod-shaped, obligate anaerobic bacterium Clostridium tetani...

, hydrophobia
Hydrophobia
Hydrophobia or hydrophobe may refer to:* Rabies, especially a set of symptoms of the later stages of an infection, in which the victim has difficulty swallowing, shows panic when presented with liquids to drink, and cannot quench his or her thirst....

 and the like.


The American author Fitz Hugh Ludlow
Fitz Hugh Ludlow
Fitz Hugh Ludlow, sometimes seen as “Fitzhugh Ludlow,” was an American author, journalist, and explorer; best-known for his autobiographical book The Hasheesh Eater ....

 used Tilden’s Extract recreationally, and wrote the book The Hasheesh Eater
The Hasheesh Eater
The Hasheesh Eater is an autobiographical book by Fitz Hugh Ludlow describing the author's altered states of consciousness and philosophical flights of fancy while he was using a cannabis extract....

(1857) about his experiences.

O.J. Kalant estimated the strength of the extract and of Ludlow’s doses as follows:

Ludlow consistently talked of “hasheesh” but in fact he took the solid extract of Cannabis Indica which was roughly twice as potent as the crude resin and ten times as potent as marijuana. A rough calculation shows that his intake was equivalent to about 6 or 7 marijuana
Cannabis (drug)
Cannabis, also known as marijuana among many other names, refers to any number of preparations of the Cannabis plant intended for use as a psychoactive drug or for medicinal purposes. The English term marijuana comes from the Mexican Spanish word marihuana...

 cigarettes per dose, i.e. at the hallucinatory rather than at the euphoriant level prevalent in contemporary North American use.


Ludlow wrote of taking as much as a drachm of the extract (3.9 grams, .14 ounces) in his largest doses — if Kalant’s figures are correct, this is equivalent to a quarter-ounce of resin or well over an ounce of herbal cannabis.
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