Philip D'Arcy Hart
Encyclopedia
Philip Montagu D’Arcy Hart, CBE
, (June 25, 1900 - July 30, 2006) was a British medical researcher and pioneer in tuberculosis treatment. Grandson of Samuel Montagu, 1st Baron Swaythling
, he became a consultant physician at University College Hospital
at the age of 34. Three years later, he joined the Medical Research Council
(MRC), and became involved with much of the MRC's early research into dust diseases in coal miners. He was a member of the MRC Streptomycin in Tuberculosis Trials Committee; their study evaluating the use of streptomycin in treating tuberculosis is generally accepted as the first randomized clinical trial. At the age of 71, Hart published a seminal paper in the Journal of Experimental Medicine
, showing the intracellular pathogen Mycobacterium tuberculosis
avoids destruction in the cell's lysosomes by circumventing these organelles altogether—a trick now known to be used by many other intracellular pathogens.
In 1941, Hart married Ruth Meyer, later a medical gynaecologist. They had a son, Oliver Hart.
Philip D'Arcy Hart died at the age of 106 in 2006.
CBE
CBE and C.B.E. are abbreviations for "Commander of the Order of the British Empire", a grade in the Order of the British Empire.Other uses include:* Chemical and Biochemical Engineering...
, (June 25, 1900 - July 30, 2006) was a British medical researcher and pioneer in tuberculosis treatment. Grandson of Samuel Montagu, 1st Baron Swaythling
Samuel Montagu, 1st Baron Swaythling
Samuel Montagu, 1st Baron Swaythling was a British banker who founded the bank of Samuel Montagu & Co.. He was a philanthropist and Liberal politician who sat in the House of Commons from 1885 to 1900, and was later raised to the peerage.Montagu was born in Liverpool as Montagu Samuel, the second...
, he became a consultant physician at University College Hospital
University College Hospital
University College Hospital is a teaching hospital located in London, United Kingdom. It is part of the University College London Hospitals NHS Foundation Trust and is closely associated with University College London ....
at the age of 34. Three years later, he joined the Medical Research Council
Medical Research Council
Medical Research Council may refer to:* Medical Research Council , a UK organisation* National Health and Medical Research Council, Australia's peak funding body for medical research...
(MRC), and became involved with much of the MRC's early research into dust diseases in coal miners. He was a member of the MRC Streptomycin in Tuberculosis Trials Committee; their study evaluating the use of streptomycin in treating tuberculosis is generally accepted as the first randomized clinical trial. At the age of 71, Hart published a seminal paper in the Journal of Experimental Medicine
Journal of Experimental Medicine
The Journal of Experimental Medicine is a peer-reviewed academic journal published by the Rockefeller University Press that publishes research papers and commentaries on the physiological, pathological, and molecular mechanisms that encompass the host response to disease...
, showing the intracellular pathogen Mycobacterium tuberculosis
Mycobacterium tuberculosis
Mycobacterium tuberculosis is a pathogenic bacterial species in the genus Mycobacterium and the causative agent of most cases of tuberculosis . First discovered in 1882 by Robert Koch, M...
avoids destruction in the cell's lysosomes by circumventing these organelles altogether—a trick now known to be used by many other intracellular pathogens.
In 1941, Hart married Ruth Meyer, later a medical gynaecologist. They had a son, Oliver Hart.
Philip D'Arcy Hart died at the age of 106 in 2006.