John R. Yates
Encyclopedia
John R. Yates III is an American chemist and professor of chemical biology
at The Scripps Research Institute
in La Jolla, California. His work is focused on developing tools and in proteomics
and he specializes in mass spectrometry
. He is probably best known for the development of the SEQUEST
algorithm for automated peptide sequencing and Multidimensional Protein Identification Technology (MudPIT).
He received a B.A. (1980) and M.S. (1983) from the University of Maine
and a Ph.D. (1987) from the University of Virginia
. He won the 1998 Pehr Edman
Award and, in 2004, won the Biemann Medal
.
Chemical biology
Chemical biology is a scientific discipline spanning the fields of chemistry and biology that involves the application of chemical techniques and tools, often compounds produced through synthetic chemistry, to the study and manipulation of biological systems. This is a subtle difference from...
at The Scripps Research Institute
The Scripps Research Institute
The Scripps Research Institute is an American medical research facility that focuses on research in the basic biomedical sciences. Headquartered in La Jolla, California, with a sister facility in Jupiter, Florida, the institute is home to 3,000 scientists, technicians, graduate students, and...
in La Jolla, California. His work is focused on developing tools and in proteomics
Proteomics
Proteomics is the large-scale study of proteins, particularly their structures and functions. Proteins are vital parts of living organisms, as they are the main components of the physiological metabolic pathways of cells. The term "proteomics" was first coined in 1997 to make an analogy with...
and he specializes in mass spectrometry
Mass spectrometry
Mass spectrometry is an analytical technique that measures the mass-to-charge ratio of charged particles.It is used for determining masses of particles, for determining the elemental composition of a sample or molecule, and for elucidating the chemical structures of molecules, such as peptides and...
. He is probably best known for the development of the SEQUEST
SEQUEST
SEQUEST is a tandem mass spectrometry data analysis program used for protein identification. Sequest identifies collections of tandem mass spectra to peptide sequences that have been generated from databases of protein sequences.-Applications:...
algorithm for automated peptide sequencing and Multidimensional Protein Identification Technology (MudPIT).
He received a B.A. (1980) and M.S. (1983) from the University of Maine
University of Maine
The University of Maine is a public research university located in Orono, Maine, United States. The university was established in 1865 as a land grant college and is referred to as the flagship university of the University of Maine System...
and a Ph.D. (1987) from the University of Virginia
University of Virginia
The University of Virginia is a public research university located in Charlottesville, Virginia, United States, founded by Thomas Jefferson...
. He won the 1998 Pehr Edman
Pehr Edman
Pehr Victor Edman was a Swedish biochemist. He developed a method for sequencing proteins, the Edman degradation.- Early life :...
Award and, in 2004, won the Biemann Medal
American Society for Mass Spectrometry
The American Society for Mass Spectrometry is a professional association based in the United States that supports the scientific field of mass spectrometry. As of 2007, the society had approximately 7000 members primarily from the US, but also from around the world...
.