The Laws of Burgos, 1512-1513 were the first laws intended to control the conduct of Spanish colonials, including Native Americans.  These laws required that natives in the empire convert to Catholicism.
        
        
     
    
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        Hernan Cortes was one of the most successful conquistadors.  He conquered the Aztecs with the support of a small Spanish force, and an army 200,000 strong of native allies.